What I know this morning

Asthma isn't as easy as its made out to be. The typical phenotypes broadly divided into just two main groups of allergic vs the non-allergic can be chucked out the window. New data is uncovering the many phenotypes of asthma. So the next time you are faced with a patient with resistant asthma who needs high doses of steroids...be aware that guidelines  don't tell you how to manage these group and tread carefully so you don't lose the trust of your patient. And the inflammatory cascade with its various interactions is a nightmare to understand.